Methylparaben
From Wikipedia, the free encyclopedia
| Methylparaben | |
|---|---|
| File:Hydroxypropyltrimonium.svg | |
|
Methyl
4-hydroxybenzoate
|
|
|
other
names
|
|
| Identifiers | |
| CAS number | 99-76-3 File:Yes check.svg |
| PubChem | 7456 |
| SMILES |
COC(=O)C1=CC=C(C=C1)O
|
| Properties | |
| Molecular formula | C8H8O3 |
| Molar mass | 152.15 g/mol |
| Related compounds | |
| Related Parabens | Ethylparaben Propylparaben Butylparaben |
| Related compounds | Methyl salicylate (orto isomer) |
| File:Yes
check.svg (what is
this?) (verify) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
|
| Infobox references | |
Methylparaben, also methyl paraben, one of the parabens, has formula CH3(C6H4(OH)COO). It is the methyl ester of p-hydroxybenzoic acid.
Contents |
Uses
| This article's factual accuracy is disputed. (October 2009) |
Methylparaben is an anti-fungal agent often used in hair gels. The compound is often found in carpules of local anaesthetic, acting as a bacteriostatic agent and preservative.
Methylparaben (also called Nipigin M, Tegosept, and Mycocten) is commonly used as in Drosophila food media. Usage of methylparaben is known to slow Drosophila growth rate in the larval and pupal stages.
Safety
Methylparaben is readily absorbed from the gastrointestinal tract or through the skin.[1] It is hydrolyzed to p-hydroxybenzoic acid and rapidly excreted without accumulation in the body.[1] Acute toxicity studies have shown that methylparaben is practically non-toxic by both oral and parenteral administration.[1] In a population with normal skin, methylparaben is practically non-irritating and non-sensitizing; however, allergic reactions to ingested parabens have been reported.[1] Methylparaben can be found in many of the leading skin/face products.
However, some concerns involving products containing parabens (including Methylparaben) are discussed in the toxicology section of the paraben article. This includes a section on allergic reactions, breast cancer, estrogenic activity, as well as paraben controversy.
References
- ^ a b c d Soni MG, Taylor SL, Greenberg NA, Burdock GA (October 2002). "Evaluation of the health aspects of methyl paraben: a review of the published literature". Food Chem. Toxicol. 40 (10): 1335–73. doi:. PMID 12387298. http://linkinghub.elsevier.com/retrieve/pii/S0278691502001072.
External links
- Methylparaben at Hazardous Substances Data Bank
- Methylparaben at Household Products Databasecs:Metylparaben
de:4-Hydroxybenzoesäuremethylester fr:4-hydroxybenzoate de méthyle hu:Metil-parahidroxibenzoát nl:Methylparabeen ru:Нипагин
